Volume 20, Issue 1 (4-2023)                   J Res Dev Nurs Midw 2023, 20(1): 8-10 | Back to browse issues page

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Barati L, Khatami S, Valizadeh M, Khoddam H. Assessing the efficacy of 10% oral dextrose in reducing pain in infants during venipuncture: A randomized controlled clinical trial. J Res Dev Nurs Midw 2023; 20 (1) :8-10
URL: http://nmj.goums.ac.ir/article-1-1424-en.html
1- Neonatal and Children's Health Research Center, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
2- Taleghani Hospital, Golestan University of Medical Sciences, Gorgan, Iran.
3- Nursing Research Center, Golestan University of Medical Sciences, Gorgan, Iran. , khoddam@goums.ac.ir
Abstract:   (1150 Views)
Background: Available evidence on the efficacy of sweet solutions for reducing pain in infants is insufficient. This study aimed to assess the effects of 10% oral dextrose on the pain of infants during venipuncture.
Methods: This randomized controlled clinical trial was done on 60 infants undergoing venipuncture. Eligible infants were randomly assigned into an intervention and control group. Two minutes before venipuncture, 2 ml of 10% oral dextrose solution and 2 ml of water were given to the intervention and control groups, respectively. The infants' pain intensity during the procedure was measured by two independent experts based on the Face, Legs, Activity, Cry, and CONSOL ability Behavioral Pain Scale. Data were analyzed using independent t-test and ANOVA tests. A P-value of ≤0.05 was considered statistically significant.
Results: The mean (±standard deviation) age of infants in the intervention and control groups were 6.37 (2.96) and 9.03 (3.10) months, respectively (P0.05). In addition, the standardized mean difference in pain score between the two groups was -0.2 (95% confidence interval: -0.30 to 0.71). Despite a significant difference (P=0.003) in the pain score between females and males, the effect of intervention after gender effect correction was not statistically significant.
Conclusion: Using 2 ml of 10% oral dextrose 2 minutes before venipuncture has a weak and non-significant effect on the pain of infants. Based on the effect size and 95% confidence interval, conducting further trials with a larger study population is recommended.
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Type of Study: Original Article | Subject: Nursing

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