Background and Objective: Effective communication is an essential characteristic of nursing care carried out as a necessity in education to empower patients. Therefore, this study aimed to determine  Nurses' knowledge, attitude and practice about  effective communication skills in Patient education.

Material and Methods: This cross-sectional study was conducted on 275 nurses selected via stratified random sampling in teaching and therapeutic centers of Esfahan University of medical sciences, 2013.We collected the data by a research-made questionnaire related to knowledge and attitude, and a checklist to observe nurses' communication skills. To analyze the data , Central indices were calculated.

Results: of 275 nurses , 86.7 %   made a friendly atmosphere with their patients and 72.2% showed positive feedback, while their knowledge about communication components were 79.6 % . They (67.3%) were active listeners and  they (96.7%) had close communication during patient education.

Conclusion: given that nurses' communication skills are moderate, we recommend holding communication-skills workshops especially in patient education.